Joanne,
It was a while ago, but I believe I was taking 300mg PTU (after many adjustments!) until my thyroid ratchetted down and I had to cut my daily dose of PTU to 150mg. I never had anything blamed on the drug, although I suspected it upset my stomach a bit. What sorts of side effects are you having?
You can email me or post here.
Elisa (phillips@pop.tiac.net)