I can understand your frustrations with all the different advice floating around. Seems the best advice would be to go by what makes YOU feel best. I think most graves sufferers who read this will agree. Only person who knows how you feel is you, yourself. What made you feel better? Taking drugs first thing upon waking? Evening? Are you switching your drugs and experimenting? This may be causing your feelings of downward slides, I don’t know. Personally, when I take my meds the same time everyday I notice that I feel much better than if I forget them or take them in off-hours.
I hope this helps you in some small way.
Jan