Its very interesting what you have to say about estrogen. I have just been diagnosed with GD. Funny thing – It came on just after I stopped taking Desogen, a High estrogen birth control pill, which I had been taking for a year to control a case of very strange acne. (of course i was also using the desogen for birth control too.) I have had strange symptoms for over a year including very high stress for no outstanding reason, acne and a change in my saliva. I’m really curious about the estrogen, but when I asked an endo friend of mine who has been working for 35 years – she said forget the estogen theory. Who Knows? I appreciate your thoughts on the matter.