Hi, Mich and Julie!
I’ve read that swelling in the eyes and feet can be a rare side effect of propylthiouracil and methimazole, so maybe general swelling could also occur in some people. Also, I thought you’d be interested to know that “With prolonged use, adverse reactions are more common.” (from NGDF’s Bulletin #23). Julie, you may be closer to the truth than you know…
Sorry that I can’t help more. I don’t have any personal experience with either drug.
Wishing you both well,
Debby
OLAF, NGDF