[Anonymous August 28, 1997 at 12:47 pm Post count: 93172]

#1157586

If you have thyroid disease and have children this may explain some
puzzing factors in their Education.

You will find out more at:- Simon Hensby who looks after the site
sent me the information below. Out of interest did anyone know about
this?

Thanet ADDers Web Site – http://adeptserv3.adept.co.uk/simonh/thadders.htm

Carol

>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>

(GRTH)
Summary:

Scientists at the National Institutes for Health (NIH) have
discovered a link between Generalized Resistance to Thyroid
Hormone (GRTH), a rare genetic disorder in which the body is
unable to appropriately use thyroid hormone, and Attention
Deficit Disorders (ADD). GRTH is believed to be relatively
uncommon; it is highly unlikely that a substantial percentage of
people with ADD have GRTH. The importance of this study is that
it provides further evidence that ADD is a neurobiological disorder.

Discussion:

NIH researchers have documented a link between ADD and GRTH, a
disorder caused by a gene coding for a defective thyroid hormone
receptor in a selected group of patients.
Researchers at NIH studied 104 members of 18 families.

THYROID DISEASE AND ATTENDTION-DEFICIT DISORDER —NOT!!
(or Maybe Just a Little)(

        Dr. P. Hauser and six colleagues from the NIH studied eighteen
families with thyroid hormone resistance. 49 members of these
families had the thyroid receptor problem, and 55 did not. 52 were
adults and 52 were children. Psychiatric interviewers scored their
ADD-like features, without knowing the results of the genetic studies.
        Of the folks with the abnormal thyroid hormone receptor gene,
30 (out of 49) met diagnostic criteria for ADD (that’s 61%); it was even
higher (70%) if you just looked at the kids. In contrast, the people who
DIDN’T have the abnormal thyroid hormone receptor gene were
unlikely to meet ADD criteria. Only two of the adults and five of the
children could be diagnosed (12.7%). This difference was very highly
statistically significant — which means it’s pretty bloody unlikely to
turn up by chance alone.

If you’d like to read more about it, the full reference is:

Authors: Hauser-P. Zametkin-A-J. Martinez-P. Vitiello-B. Matochik
J-A. Mixson-A-J. Weintraub-B-D.
Institution: Molecular and Cellular Endocrinology Branch, National
Institute of Diabetes and Digestive and Kidney Diseases, National
Institutes of Health, Bethesda, MD 20892.
Title: Attention deficit-hyperactivity disorder in people with
generalized resistance to thyroid hormone [see comments].
Accompanying editorial: Comment in: N Engl J Med 1993 Apr 8;
328(14):1038-9.
Source: N-Engl-J-Med. 1993 Apr 8. 328(14). P 997-1001.
Full Journal Title: NEW ENGLAND JOURNAL OF MEDICINE.<<<<<<<
<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<

[Anonymous August 28, 1997 at 3:16 pm Post count: 93172]

#1053996

I have noticed that there are several individuals on the BB that
have alluded to the fact that they have kids with ADHD. I have a
five year old son who we suspect may have ADHD. Is there a link between
GD and ADHD?? Is anyone on the BB aware of any studies regarding this
matter? Any information regarding this matter would be greatly
appreciated.

Best Regards to you all,

James

[Author]

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