Hi Richard, Be suer and ask all your questions when you go for your appointment and keep us posted OK? I am especially curious what he will say about the depression. I hate to be sexist, but I have a feeling he may tke it a bit more seriously since you are a man. Maybe knowing about it now will keep it from becoming a big issue. I hope and pary your synthroid continues to work and get you back to feeling well again. Take care..