I tried methimazole for about a year. In the meantime I developed eye symptoms. Due to the eye symptoms RAI was not an option so I had TT. Easy surgery and a God Send as pallipary carcinoma was found. As I was not in the high risk group , no cancer in my family, non smoker, etc it was a surprise to everyone. Either way you will most likely be on medicine the rest of your life. The adjustment to synthriod is much easier than the ups and downs I experienced with methimazle. Good luck and hang in there.