I have had GD for nine years and have been on Methimazole (1mg/ day). I am recently having the same issues with leg cramps, muscle aches, and cold chills. I have been told by my Endo not to worry about chills, but I see that allergic side effects of Methimazole (Tapazole) can cause this. As for leg cramps I was told by a homeopathic chiropractor to take magnesium and drink more water, this does seem to help. Also Midol works for leg cramps. Our thyroid regulates several organs in our bodies, including heart rate (that cause femoral hand tremors), hormones, etc.
