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  • Carito71
    Participant
    Post count: 333

    General information from ncbi about Perchlorate. Very interesting. I wonder if Graves cases are less in parts on earth with Perchlorate in drinking water.

    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2681191/

    Carito71
    Participant
    Post count: 333
    in reply to: Remission #1175652
    smtucker wrote:
    What does remission mean in regards to Graves Disease? Does this mean no drug management or something else?

    [Yea, a dumb newbie question.]

    Good question. No symptoms, normal thyroid levels without medications? It might be different per Dr.?

    Carito71
    Participant
    Post count: 333
    in reply to: Remission #1175651
    goodfriendjen wrote:
    I think it’s because I just want to move on with my life and have kids and not worry that the GD will resurface one day. But I don’t know if that’s good enough reason. Will having the TT make the life I want to move on with a harder road that dealing with recurring remissions? I am so unsure…

    GD will always be there until there is a way to remove the autoimmune problem.

    Without a thyroid you will no longer experience the hyperthyroid problems if all of the thyroid tissue is removed. If you achieved remission it doesn’t necessarily mean that you will have recurring remissions. Kimberly earlier mentioned of someone named James who has been on remission for 9 years.

    All three treatments will have their pros and cons. Surgery after all is surgery and it has its risks that way (parathyroid involvement, anesthesia, recovery from surgery, etc).

    If you will be able to have a family sooner than later with a TT and it is very important to you and your husband to have a family as soon as possible then wanting a TT for that reason is a good reason. If you go that route please inform yourself about what the surgery will entitle and what other GD symptoms you might still have to deal with even with a TT.

    I just left an article that you might enjoy reading.

    I’m wishing you all of the best making the right decision for you.

    Caro

    Carito71
    Participant
    Post count: 333
    in reply to: Remission #1175650

    This is a good article about remission:

    Title:
    “Remission of Graves’ disease during anti-thyroid drug therapy. Time to reconsider the mechanism?”

    http://www.eje-online.org/content/155/6/783.full

    Caro

    Carito71
    Participant
    Post count: 333
    in reply to: Remission #1175646

    Very interesting article Naisly. After the immune system and GD, pregnancy is another one of the things I like to read about.

    Carito71
    Participant
    Post count: 333
    in reply to: Remission #1175645

    After reading Shirley’s comment, I would like to add one more Dr. to consult, if you haven’t yet, a Reproductive Endocrinologist (RE). A RE can tell you how things are looking with your fertility and about how long he recommends waiting. A woman’s age doesn’t always go hand in hand with her fertility.

    Caro :)

    Carito71
    Participant
    Post count: 333
    in reply to: Remission #1175644

    goodfriendjen,

    Hello. You are welcome. We hope that with all of these information you can make the best decision for you.

    As for the remission statement from your Dr., did she want you to push back the TT because she thinks you might go into remission or because of something else? Did she think that you might go into remission because as you mentioned, your thyroid #s are in range? I personally think that the TSIs being at 300 are a concern and is unknown when they will reach a normal range (I have heard that the lower and closest to 0 the better if within normal range before stopping Rx). Maybe she has seen patients whose TSIs get lower when the thyroid #s are in range. These, I believe, are things to ask your Dr. so that you can get an idea as to how he knows that you might go into remission.

    I think that it is fair to say that anyone who has started responding positive to the medication “might go into remission” because it is a vague statement.

    It is unfortunate to be hit with GD right at a time when you have plans that some times are harder to achieve if more time goes by (pregnancy in the 30s). I personally think that the health of the woman is very important before pregnancy can be achieved, carried for 9 months, and be there ready to take care of a new life. Your health should be your priority at this moment because once you gain your health back and are stable on it, you can proceed with a pregnancy. I know, time is of the essence. I think that you, your husband, and your Dr need to sit down and go over everything again. What does she mean by “might achieve remission”? Is there a formula she is using to know how long before then? (I doubt it). Can you wait that long? Are you willing to go through surgery, RAI? When a difficult decision is in your way, a wise man once said, take a look at yourself years from now and decide what you will be able to live with and live without.

    So my question to you is, what can you live with and what can you live without when it comes to this situation? Have backup plans also because things don’t always go as planned. Get statistics and #s to make sure you know your odds.

    When it comes to parenthood, there are many ways of getting there. Also, as some will tell you, pregnancy is achievable with stable GD so there is hope for parenthood one way or another …. just a thought. :)

    Caro

    P.S. The billirubin is liver related and Methimazole can some times cause liver problems. A liver panel, AST/ALT levels can show if your liver is being affected.

    Carito71
    Participant
    Post count: 333
    Kimberly wrote:
    @Caro – Yes, TSI is specific to the antibodies that cause *stimulation* of the thyroid gland, while TRAb does not differentiate between blocking and stimulating antibodies. Anti-TPO antibody testing is more commonly used to diagnose a patient who is hypO with Hashimoto’s thyroiditis – although a fairly large percentage of Graves’ patients will test positive for these antibodies as well. Hope this helps!

    Thank you Kimberly.

    Carito71
    Participant
    Post count: 333
    in reply to: Remission #1175637
    goodfriendjen wrote:
    The last time I had my TSI’s measured it was Oct 30th and they were still in the 300’s. My TRAb was 6. So the antibodies are still elevated.

    In this case I would be worried about stopping treatment. I wonder how your Dr. defines “remission”.

    Carito71
    Participant
    Post count: 333
    in reply to: Remission #1175636

    goodfriendjen,

    Since you mentioned pregnancy, I thought that you might be interested in this article:

    http://www.thyroid.org/wp-content/uploads/patients/brochures/Thyroid_Dis_Pregnancy_broch.pdf

    Caro

    Carito71
    Participant
    Post count: 333
    ProActivePatient wrote:
    I found that after I had RAI my TSH remains low or suppressed, but my Free T3 and Free T4 are in range. My Endo (since fired) said I’m hyper still because of the low TSH and wanted to dose my synthroid based on the TSH result. What do you think? What has your experience been?

    My Dr. always goes by what my Free T4 is doing. He tests TSH as well but he seems to concentrate on the Free T4s more. The TSH is the hormone produced by the pituitary and the Free T4/T3 is produced by the thyroid (these 2 are the ones that make us feel sick and that make our metabolism go crazy), so, just knowing that information makes sense as to why Free T4/T3 is more important to use for adjustment purposes.

    I would have fired him too if all he cared about was the TSH.

    Hope all gets resolved soon.

    Caro

    Carito71
    Participant
    Post count: 333
    gatorgirly wrote:
    My endo only ticks off the TSH and T4 boxes when he sends me a lab slip every six weeks. I always check off T3, too.

    I have been temped to do this also. Finally my Dr. ordered free T3s on his own for next labs. I’m glad he did b/c I was going to mention it. I didn’t mention it last time because I got him to run TSIs. Some times I feel like I’m playing a game of give and take :|

    Carito71
    Participant
    Post count: 333
    in reply to: Remission #1175633

    It is good though that your Dr. thinks that you might be on the road to remission. That is really good news. :)

    Carito71
    Participant
    Post count: 333
    in reply to: Remission #1175631

    Hello.

    You might find this link interesting:

    http://www.gdatf.org/forum/topic/43092/

    You stated:

    goodfriendjen wrote:
    All my numbers are in range and she just lowered me to 5 mg methimazole from 10 mg.

    Does this include your TSI #s.

    Also, if I understand it correctly, the 20-30% for the US is with a 2 years treatment and the 50-60% for Europe is with a 5 years treatment. So maybe it is related to the amount of time the person is on treatment (maybe time allows the TSIs to get lower). The Japanese study, for what my Dr. mentioned, appears to be higher maybe because of genetic reasons.

    Before discontinuing the Methimazole, I think that it is wise to find out what the TSIs are. My Dr. told me that with TSIs still elevated that it didn’t matter if the thyroid hormone #s were in range because the TSIs would continue to elevate them.

    I hope that this information helps.

    Caro

    Carito71
    Participant
    Post count: 333

    Welcome ProActivePatient.

    Thank you for wanting to share information. I’m one of those sponges who likes to learn as much about GD as possible.

    Kimberly, it is ok sharing the link through PM, right?

    Caro

Viewing 15 posts - 16 through 30 (of 301 total)