I had RAI in April 2004 at age 46, started Levoxyl that summer and haven’t given it much thought since. We’ve tinkered with my dose but I have been stable enough that when my endocrinologist moved away I decided to let my internist supervise and it’s working out fine. I did gain about 15 pounds after RAI, but with regular exercise I’m holding the weight steady and haven’t given up hope of losing it. For me the biggest inconvenience is having to wait 2 hours after taking Levoxyl before I can have soy milk on my cereal. (I don’t drink cow’s milk – lactose issues.) Lately I’ve been using rice milk instead if I can’t wait 2 hours. Bottom line, I’d do it the same way all over again and feel grateful that management has been so easy.