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  • shakira7
    Participant
    Post count: 82

    Hello everyone,

    I just received my TPO thyroid anti-body test results in my mail.

    Does TPO level have any relation to the Graves disease?

    My results say the following:
    Anti-thyroid peroxidase antibodies – 0.60 IU/mL

    the next column say Normal Range : 0.00 – 9.00 IU/mL

    Does anyone know what this implies?

    Thank you.

    Kimberly
    Keymaster
    Post count: 4294

    Hello – TPOab (Thyroid Peroxidase Antibodies) are directed against TPO, an enzyme that is involved in thyroid hormone synthesis. The presence of TPOab is considered a potential marker for autoimmune thyroid disease (Graves’ or Hashimoto’s thyroiditis), but is not specifically diagnostic for Graves’ disease. Some people actually have elevated TPOabs with completely normal thyroid function, although this situation is usually watched closely to see if thyroid issues do eventually develop.

    The key antibody tests for Graves’ are TRAb (Thyrotropin Receptor Antibody) or TSI (thyroid stimulating immunoglobulin).

    Carito71
    Participant
    Post count: 333

    Shakira7 … its me again :)

    I had an elevated TPOab last year. At the time my TSH was within the normal range though on the low side of normal. I was told to check my thyroid periodically. In Feb of this year I had my TSH tested again and again it was within the normal range (low side of normal). Late May I became tired and in early June I had to go to the ER with tachycardia. At the ER they ran TSH, fT3, fT4, TSI, and TPOab. All results pointed towards hyperthyroidisim. Since my TSI was elevated I was told I have Graves’ D. I have been on Methimazole since then.

    Caro :)

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