[SueAndHerZoo]

#1060256

Seriously?????? I’m sitting here feeling a lot of the symptoms I feel whenever we change my dose of Levothyroxine but this last tweak ws such a tiny change I’m finding it hard to believe I would notice (and of course my endo tells me I can’t possibly be feeling it). I was at 112 mcg. per day and was still a little hyper so he offered me the option to alternate days of 100 mcg. and 112 mcg. I started that 7 days ago and last night and today I’m feeling anxious, panicky, increased heart rate, and oh so HOT. Also got that irritable, ready-to-cry feeling and this is exactly what I felt for weeks last time we changed doses.

I know there have been members of this forum who tell me that, yes, even the tiniest change can cause this, so please remind me again. That will help me just accept and breathe through this rather than obsessing over why I feel like this.

And I guess the other question is, if I am THAT sensitive to dose changes, is alternating days a bad idea? I know the med has a long half-life so it’s the long term dosage that matters, but this last change only averages out to a change of 6 mcg. a day which seems miniscule to me. Am I super sensitive to this stuff?????

Thanks for letting me vent and for any words of comfort that this too shall pass.
Sue

[Raspberry]

#1181572

I am the same way super-sensitive to changes though in my case it’s miniscule mmi changes! It really threw off my initial dose changes because I and my endo believed my accelerating symptoms meant the dose change was a mistake. Now I know to expect to ride out about two weeks of hell even if it is the right thing to do. For me with the mmi it’s been very important to have exactly the same dose every day at the same time. Still it gets harder with the smaller changes. I tried a compounding pharmacy once and it was great – except for the expense. I wonder if you could get compounded levo at 106mcg?

[SueAndHerZoo]

#1181573

Thanks for letting me know I’m not alone, different drug but same response.

I suppose I could try to have a 106 pill made for me but I won’t even think about that until we determine if 106 is where I need to be, and of course we won’t know that for about 7 weeks. I’m not sure if the daily dose change is causing the issue or if it’s the overall “lowering” of my cumulative dose that’s doing it. I almost think it’s the cumulative because the symptoms didn’t start until last night, day 7 of the change. If it were the alternating days causing the problem I probably would have noticed it sooner, but who the heck knows.
Sue

[ChristinaDe]

#1181574

Hi Sue! Sorry you’re another one of us who gets dose-change-itis! I hate that syndrome. You asked for it, so I’ll do it – I’ll remind you that for some of us lucky souls dose changes can be really rough…we are just THAT sensitive when it comes to thyroid hormone levels! And I’ll also remind you that this is temporary, you’ll eventually level out on this dose & those pesky change symptoms will subside.

Another thing…I did notice that as I got closer to my normal…and therefore my level actually moved less w/ each change…the dose change symptoms were a bit more dramatic. Strange. I don’t get it. But it’s definitely what I felt. So if you’re anything like me, feeling so awful w/ the small adjustment may actually be good news?!? Maybe you’re getting super close to that magical adjustment to “just right”? I really hope so.

Your question about whether alternating doses when you seem to be sensitive to any changes in your levels is an interesting one. I don’t have any personal experience w/ doing that & I’ve not read anything about it either. I see both of your points. With the long half-life, it seems that, on paper at least, it shouldn’t have a negative effect. But you do have to wonder if it somehow could impact someone super sensitive to T4 changes. I know that on paper a TSH of 3.6 shouldn’t make me feel super hypo, but it does. I can definitely see why your endo wants to pursue that path next tho. You’re so close to therapeutic, but not quite where. I truly hope this gets you there. And soon. And it really sounds like you’re another one w/ an endo who is listening & willing to tailor your meds to YOU! Good news there!!

[SueAndHerZoo]

#1181575

Thanks, Christine. I think I’ll print out your reply and keep it in my purse with some of the other valuable and comforting snippets I’ve taken from here.

I told myself that since this recent change is so small that I wouldn’t feel much in the way of symptoms, and now that I am feeling them I’m telling myself they probably won’t last as long as usual since it’s a tiny change. That’s my story and I’m sticking with it.

I truly think this dose will be the “winner” because I could have stayed at 112 every day but wanted to bring down the anxiety and insomnia a notch. If alternating every other day isn’t causing me problems then I think I’ll be great in a few weeks. Again, that’s my story and I’m sticking with it. I’m projecting good things in the hopes the Universe (and my body) will help me speak the truth.

Thanks for the reassurance.
Sue

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