Hi, there is a very helpful discussion with the subject line of "New to Replacement, a couple of questions." It began in January 7. There a a good discussion of your question, and good info in each reply. Bobbie and Sky have responded to your questions specifically, with some reasons for the timing, and for taking it on an empty stomach with a whole glass of water..in the morning. I know my stomach is really empty then!
I do this, then have a cup of coffee, and I don’t wait. i also put a bit of milk in my coffee, and don’t worry about it, cause I do the same thing everyday. I don’t want to eat when I get up, so it is easy for me to wait 1/2+ hour before eating breakfast. Check out those comments. Shirley