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    Wow – thank you for that info. I really know very little about mast cells and histamine but it’s definitely something I should learn more about as apparently it affects my TSH and my colitis. I also had no idea there were seasonal fluctuations with thyroid levels – very interesting!

    That information will definitely be helpful the next time I see my levels are only a little off and I’m not really experiencing any symptoms, at that point perhaps I’ll wait to stay at the same dose with the expectation that it will regulate as the year goes on. So now to be MUCH more careful with gluten and see how it goes. Thanks again for the reply!