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    This makes sense. Mast cells, which secrete histamine, affect T3 and gluten intolerance also has a histamine connection. It could be the histamine levels and activation of mast cells that cause your problem. It could also be an absorption issue. Also there is a seasonal variation in TSH levels most people are unaware of, trends higher in winter and lower in summer, which might cause a seasonal, maybe unnecessary, shift in your dose – unnecessary because people with normal thyroids see this same seasonal variation. Certainly worth a trial of total gluten elimination.