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    My own personal opinion based on my own experience is that you may be reacting to the Levothyroxine. I was on Armour for 30 plus years and felt great until they reformulated the product. My numbers started going crazy so the doctor put me on Levothyroxine. While it did stabilize my numbers, I never felt quite well or right on the medication. I’m now on a medication made by a compounding pharmacy called Nature-throid which is on prescription. I feel SO much Better after 6 weeks. I know there are many people on Synthroid or Levothyroxine that are fine but there are many people who don’t feel well on it. As far as the depression, often times it is the thyroid issues that contribute to that from what my Endocrinologist once told me. I think if you get on the right medication, you may start to feel better. Hope this helps. It is not in your mind psychologically; it is actually physiological.