Online Facilitator
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    Hello – We’ve heard mixed messaging as to whether T3 needs to be taken on an empty stomach. (T4 *definitely* does). You might check with your doctor about this and also ask whether 4:00 a.m. is the best time for dosing – T3 is the more powerful and active form of thyroid hormone, and you might not want a large dump of thyroid hormone if you are going back to bed!

    The prescribing info for generic T3 does have a section on antidepressants and drug interactions, so that would be worth a conversation with your doctor as well: