4 hours after levothyroxine before you take calcium supplements but I would not worry about milk, lattes, etc if one hour post levothyroxine. I have coffee with cream and sometimes cereal with milk, no problems. Be aware that proton pump inhibitors, like Nexium, etc can interfere with absorption. Coffee actually interferes with absorption, but as long as you are consistent, like drink coffee every day or do not drink coffee, your dose will stabilize to reflect your habits.