The only drawbacks I know about PTU are that first, it is short-lived, so you typically must take it three times a day, and you also need to do your very best to make those time periods standard in order to have the best possible chance of keeping your levels steady. Second, it tastes foul. Some people either bury it in food that tastes good, or follow it with something they like that is very strong-tasting.
Other than that, it works slightly differently to produce the same result, so I’m not sure whether you would experience the same difficulties, but it’s probably worth a shot. We’re all so different, it’s really impossible to say what you might encounter. Most of the big side effects are the same across the two meds, but you’re talking about "secondary" effects (not all that common), so there is a chance that PTU would not cause those same issues.
